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Conquering Psoriasis: Understanding, Management, and Hope

 

Dermatology_Psoriasis

Though psoriasis is a widely recognized skin condition, its true nature remains elusive to most. Yet, for those living with psoriasis, its far-reaching effects span across various facets of life-shaping appearance, self-assurance, professional pursuits, physical activities, and personal connections. Here, delve into ten lesser-known revelations about the complexities of psoriasis.

What is the extent of the affected population?
In September 2021, estimates suggested that around 2-3% of the world's population was grappling with psoriasis. Psoriasis primarily has genetic roots—it's a hereditary condition. However, this doesn't necessarily imply that parents of individuals with psoriasis will have experienced it themselves. Rather, it's the interplay of specific genetic factors that could act as the catalyst. Given that altering our genes isn't feasible, the emphasis of treatments lies in minimizing and pre-empting skin-related complications as they arise.

What happens to the skin?
The skin impacted by psoriasis undergoes distinct changes. It becomes marked by raised, reddish patches known as plaques, often covered by silvery scales. These patches can appear on various parts of the body, such as elbows, knees, scalp, and lower back. The affected skin might feel itchy, painful, or even crack and bleed. Additionally, psoriasis can affect the nails, causing them to thicken, develop ridges, or separate from the nail bed. The severity of these symptoms can vary widely from person to person and even over time for the same individual.

Treatment
The primary objective of psoriasis treatments is to curtail the rapid proliferation of skin cells and eliminate the formation of scales. Available options encompass topical applications like creams and ointments, light-based interventions such as phototherapy, and administration of medications via oral or injection routes.

Topical therapy encompasses several options:
Corticosteroids: Frequently prescribed for mild to moderate psoriasis, these drugs are available in various formulations such as oils, creams, ointments, lotions, gels, foams, sprays, and shampoos.

Vitamin D Analogues: Synthetic versions of vitamin D, like calcipotriene (Dovonex, Sorilux) and calcitriol (Vectical), slow down the growth of skin cells. They can be used alone or in conjunction with topical corticosteroids.

Salicylic Acid: Shampoos and scalp solutions containing salicylic acid reduce scaling in scalp psoriasis. They come in nonprescription or prescription strengths and can be used alone or in combination with other topical treatments to enhance the absorption of medication.

Coal Tar: Coal tar mitigates scaling, itching, and inflammation. It's available in both nonprescription and prescription strengths and comes in various forms like shampoo[RT1] , cream, and oil. It's worth noting that coal tar products can be irritating to the skin, and they can also stain clothing and bedding while emitting a strong odor.

Light therapy
Phototherapy, also known as light therapy, stands as an initial treatment for moderate to severe psoriasis, either independently or alongside medications. This method entails subjecting the skin to carefully regulated doses of natural or artificial light. Consistent sessions are required for effective results.

Psoriatic arthritis is a chronic inflammatory condition that affects some individuals with psoriasis, a skin disorder characterized by scaly patches and redness. Psoriatic arthritis primarily impacts the joints, causing pain, swelling, and stiffness. It can also affect other parts of the body, such as the skin, nails, and even organs.

Are there any potential risks associated with psoriasis in the long term?
Indeed, individuals with psoriasis face a slightly elevated risk of long-term complications, notably including an increased likelihood of heart attacks and strokes. This risk aligns with other chronic inflammatory conditions, as prolonged inflammation can contribute to the development of cardiovascular issues. The underlying mechanism involves the presence of low levels of cytokines—natural inflammatory substances—that can enter the bloodstream and contribute to arterial plaque buildup, leading to cardiovascular diseases. If you suspect you have psoriasis or require guidance and treatment, it's advisable to consult a dermatologist.

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